Compounds > N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide
Page last updated: 2024-09-05

N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide and pci 32765

N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide has been researched along with pci 32765 in 1 studies

Compound Research Comparison

Studies
(N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide)		Trials
(N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide)		Recent Studies (post-2010)
(N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide)		Studies
(pci 32765)		Trials
(pci 32765)		Recent Studies (post-2010) (pci 32765)
9071,9262431,895

Protein Interaction Comparison

ProteinTaxonomyN-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide (IC50)pci 32765 (IC50)
Testosterone 17-beta-dehydrogenase 3Rattus norvegicus (Norway rat)0.0028
Solute carrier family 22 member 3Homo sapiens (human)7.9
Epidermal growth factor receptorHomo sapiens (human)0.0402
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)0.0104
Cytochrome P450 1A2Homo sapiens (human)0.019
Tyrosine-protein kinase LckHomo sapiens (human)0.018
Tyrosine-protein kinase FynHomo sapiens (human)0.096
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)5.545
Tyrosine-protein kinase YesHomo sapiens (human)0.0065
Tyrosine-protein kinase LynHomo sapiens (human)0.2
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)0.0262
Tyrosine-protein kinase HCKHomo sapiens (human)0.0095
Cytochrome P450 3A4Homo sapiens (human)0.089
Tyrosine-protein kinase FgrHomo sapiens (human)0.0021
Cytochrome P450 2C8Homo sapiens (human)3.9595
Cytochrome P450 2D6Homo sapiens (human)0.0769
Cytochrome P450 2C9 Homo sapiens (human)6.0643
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)0.0768
Cytochrome P450 2B6Homo sapiens (human)0.101
Cytochrome P450 2C19Homo sapiens (human)0.0769
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)0.073
Tyrosine-protein kinase CSKHomo sapiens (human)0.0023
Tyrosine-protein kinase TecHomo sapiens (human)0.0092
Tyrosine-protein kinase TXKHomo sapiens (human)0.0025
Tyrosine-protein kinase FRKHomo sapiens (human)0.0541
Tyrosine-protein kinase BlkHomo sapiens (human)0.0004
Cytoplasmic tyrosine-protein kinase BMXHomo sapiens (human)0.002
Tyrosine-protein kinase JAK3Homo sapiens (human)0.0411
Tyrosine-protein kinase BTKHomo sapiens (human)0.0422
Tyrosine-protein kinase ITK/TSKHomo sapiens (human)0.0471
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)4.4
Protein-tyrosine kinase 6Homo sapiens (human)0.018
Receptor tyrosine-protein kinase erbB-4Homo sapiens (human)0.0066
Nuclear receptor subfamily 4 group A member 3Homo sapiens (human)0.078
Peroxiredoxin-like 2AHomo sapiens (human)0.9
Platelet glycoprotein VIHomo sapiens (human)0.12

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1

Other Studies

1 other study(ies) available for N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide and pci 32765

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013